2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-169790
    Phomarin
    		Inhibitor
    Phomarin is an inhibitor for dihydrofolate reductase (DHFR), and exhibits potential antimalarial activity.
    Phomarin
  • HY-N1584AR
    Halofuginone hydrobromide (Standard)
    		Inhibitor
    Halofuginone (hydrobromide) (Standard) is the analytical standard of Halofuginone (hydrobromide). This product is intended for research and analytical applications. Halofuginone (RU-19110) hydrobromid, a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a Ki of 18.3 nM. Halofuginone hydrobromid is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activity. Halofuginone hydrobromid is also a potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated and store-operated Ca2+ channels. Halofuginone hydrobromid has anti-malaria, anti-inflammatory, anti-cancer, anti-fibrosis effects.
    Halofuginone hydrobromide (Standard)
  • HY-W097659
    Antileishmanial agent-32
    		Inhibitor
    Antileishmanial agent-32 (Compound 12) exhibits a weak antileishmanial activity that inhibits stationary promastigote forms of L. amazonensis with an IC50 >15 μM. Antileishmanial agent-32 exhibits cytotoxicity towards murine macrophages.
    Antileishmanial agent-32
  • HY-116144R
    Picaridin (Standard)
    		Inhibitor
    Picaridin (Standard) is the analytical standard of Picaridin. This product is intended for research and analytical applications. Picaridin (Lcaridin) is a broad spectrum arthropod repellent. The repellent and deterrent activities of Picaridin involve olfactory sensing in mosquitoes, and ticks, via their interactions with odorant receptor proteins.
    Picaridin (Standard)
  • HY-W020111
    7-Chloro-4-(piperazin-1-yl)quinoline
    		Inhibitor 98.63%
    7-Chloro-4-(piperazin-1-yl)quinolone is an important scaffold in medicinal chemistry. 7-Chloro-4-(piperazin-1-yl)quinolone is a potent sirtuin inhibitor and also inhibits the serotonin uptake (IC50 of 50 μM). 7-Chloro-4-(piperazin-1-yl)quinolone exhibits antimalarial activity on D10 and K1 strains of P. falciparum with IC50s of 1.18 μM and 0.97 μM, respectively.
    7-Chloro-4-(piperazin-1-yl)quinoline
  • HY-B0273R
    Sulfadiazine (Standard)
    		Inhibitor
    Sulfadiazine (Standard) is the analytical standard of Sulfadiazine. This product is intended for research and analytical applications. Sulfadiazine is a sulfonamide antibiotic with antimalarial activity. Sulfadiazine can be used for toxoplasmosis research.
    Sulfadiazine (Standard)
  • HY-B0828
    Triazophos
    		98.70%
    Triazophos, a non-systemic insecticide and acaricide that acts as an acetylcholinesterase (AChE) inhibitor, covalently and irreversibly binds to the acetylcholine binding site, thus blocking the hydrolysis of acetylcholine and leading to hyperexcitability; it is effective against a variety of soil insects and mites, including aphids, thrips, midges, beetles, Lepidoptera larvae, cutworms, and spider mites in crops such as ornamentals, cotton, rice, maize, soybeans, oil palms, olives, and coffee.
    Triazophos
  • HY-B0094R
    Artemisinin (Standard)
    		Inhibitor
    Artemisinin (Standard) is the analytical standard of Artemisinin. This product is intended for research and analytical applications. Artemisinin (Qinghaosu), a sesquiterpene lactone, is an anti-malarial agent isolated from the aerial parts of Artemisia annua L. plants. Artemisinin inhibits AKT signaling pathway by decreasing pAKT in a dose-dependent manner. Artemisinin reduces cancer cell proliferation, migration, invasion, tumorigenesis and metastasis and has neuroprotective effects.
    Artemisinin (Standard)
  • HY-14749AS
    Pyronaridine-d4 tetraphosphate
    Pyronaridine-d4 (tetraphosphate) is the deuterium labeled Pyronaridine tetraphosphate. Pyronaridine tetraphosphate is an orally active Mannich base anti-malarial agent. Pyronaridine tetraphosphate is active against P. falciparum and Echinococcus granulosus infection.
    Pyronaridine-d<sub>4</sub> tetraphosphate
  • HY-B1120
    Temephos
    		Inhibitor 99.01%
    Temefos is an organophosphate larvicide, used to treat water infested with disease-carrying insects including mosquitoes, midges, and black fly larvae.
    Temephos
  • HY-14895A
    Fabomotizole hydrochloride
    		Inhibitor 99.95%
    Fabomotizole (CM346) hydrochloride is a compound with anxiolytic and neuroprotective activities. Fabomotizole (CM346) hydrochloride also has activity against Giardia lamblia and has the potential to inhibit giardiasis.
    Fabomotizole hydrochloride
  • HY-129671
    Polypodine B
    		Inhibitor 98.60%
    Polypodine B is a natural ecdysone ester isolated from the bark of Dacrydium intermedium. Polypodine B significantly inhibits the activity of Acanthamoeba castellani. Polypodine B has moderate antifungal activity. Polypodine B can be used for research on parasitic diseases and fungal infections.
    Polypodine B
  • HY-B1004
    Dinitolmide
    		Inhibitor 99.66%
    Dinitolmide (Zoalene) is an orally active anticoccidial agent used as a fodder additive. Dinitolmide has a wide anticoccidial spectrum with no effect on host immunity. Dinitolmide mainly acts on the first generation merozoite stage of coccidia and also has an inhibitory effect on the sporulation process of oocysts. Dinitolmide has anti-Toxoplasma gondii effect in vitro with an EC50 of 3.625 μg/mL. Dinitolmide can be used to inhibits infections caused by Eimeria tenella.
    Dinitolmide
  • HY-B1207R
    Urethane (Standard)
    		Inhibitor
    Urethane (Standard) is the analytical standard of Urethane. This product is intended for research and analytical applications. Urethane (Ethyl carbamate), the ethyl ester of carbamic acid, is a byproduct of fermentation found in various food products. Urethane has the ability to suppress bacterial, protozoal, sea urchin egg, and plant tissue growth in vitro.
    Urethane (Standard)
  • HY-B1703S
    Nifursol-13C6
    		Inhibitor 99.60%
    Nifursol-13C6 is the 13C6 labeled Nifursol (HY-B1703). Nifursol (Standard) is the analytical standard of Nifursol (HY-B1703). This product is used for research and analytical applications. Nifursol is an orally active veterinary antibiotic. Nifursol inhibits Histomonas meleagridis. Nifursol prevents histomoniasis in turkeys. Nifursol is widely used in studies of Escherichia coli gastroenteritis in Salmonella-infected poultry and aquatic animals.
    Nifursol-<sup>13</sup>C<sub>6</sub>
  • HY-W780803
    (Z,E)-9,12-Tetradecadienol
    		Inhibitor
    (Z,E)-9,12-Tetradecadienol is a synthetic enhancer of male Ephestia cautella attraction.
    (Z,E)-9,12-Tetradecadienol
  • HY-B0840R
    Chlorfenapyr (Standard)
    Chlorfenapyr (Standard) is the analytical standard of Chlorfenapyr. This product is intended for research and analytical applications. Chlorfenapyr is a pyrrole insecticide. Chlorfenapyr has a mode of action: the mixed function oxidase oxidizes and removes the Nethoxymethyl group to form the active metabolite, CL 303268. Chlorfenapyr is used for termite control and crop protection against a variety of insect and mite pests.
    Chlorfenapyr (Standard)
  • HY-W010254
    4′-Hydroxy-2′-methylacetophenone
    		Inhibitor 99.90%
    4′-Hydroxy-2′-methylacetophenone, an aroma compound of red wines, is isolated from cv. Bobal grape variety. 4′-Hydroxy-2′-methylacetophenone has ciliate toxicity. 4′-Hydroxy-2′-methylacetophenone inhibits the growth of T. pyriformis, with an IC50 of 0.65 mM.
    4′-Hydroxy-2′-methylacetophenone
  • HY-32004
    Coumalic acid
    Coumalic acid is an inhibitor of human carbonic anhydrase (hCA) (KI = 0.073 μM for hCA IX; KI = 0.083 μM for hCA XII). Coumalic acid is a valuable platform compound which can be prepared from malic acid. Coumalic acid can be used in the flavorings, fragrances and cosmetics industries, as polymer components, and pharmaceutical scaffolds. Coumalic acid displays antibronchial and antimalarial activity.
    Coumalic acid
  • HY-W111370
    2-Nitroamino-2-imidazoline
    		Inhibitor 98.0%
    2-Nitroamino-2-imidazoline is an intermediate in the synthesis of the neonicotinoid insecticide Imidacloprid (HY-B0838).
    2-Nitroamino-2-imidazoline
Parasite Isoform Comparison

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